Dr. Leonie Müller (née Nüßer)

Room: 109
Phone: +49 (0) 241 / 80 – 23686
Institute for Environmental Research, RWTH Aachen University Kackertstraße 10 52072 Aachen Germany

Curriculum vitae

Since 2021: Postdoc at the Institute for Environmental Research (RWTH Aachen University)

Since 2021: Policy officer at Altertox, Brussels.

2015-2019: PhD (Dr. rer. nat.) at the Institute for Environmental Research at RWTH Aachen University

Thesis: ‘Advancing evaluation and applicability of zebrafish embryo behavior assays through sophisticated mathematical methods and innovative technology for on-line monitoring and assessment’

2015: M.Sc. Ecotoxicology at RWTH Aachen University

Thesis: ‘Assessment of the toxicogenomic potential of complex industrial wastewater effluents in zebrafish using RNA-sequencing-by-synthesis technology’

2011: B.Sc. Biology at RWTH Aachen University

Thesis: ‘Acute and mechanism specific toxicity of complex industrial wastewater effluents’

Peer-reviewed publications

Johann, S., Nüßer, L., Goßen, M., Hollert, H., & Seiler, T. B. (2020). Differences in biomarker and behavioral responses to native and chemically dispersed crude and refined fossil oils in zebrafish early life stages. Science of The Total Environment, 709, 136174.

Johann, S., Esser, M., Nüßer, L., Altin, D., Hollert, H., & Seiler, T. B. (2020). Receptor-mediated estrogenicity of native and chemically dispersed crude oil determined using adapted microscale reporter gene assays. Environment international, 134, 105320.

Skulovich, O., Ganal, C., Nüßer, L. K., Cofalla, C., Schuettrumpf, H., Hollert, H., Seiler, T.-B. & Ostfeld, A. (2018). Prediction of erosional rates for cohesive sediments in annular flume experiments using artificial neural networks. H2Open Journal, 1(2), 99-111.

Eichbaum, K., Brinkmann, M., Nuesser, L., Gembé, C., Ohlig, M., Buchinger, S., Reifferscheid, G., Hecker, M., Giesy, J. & Hollert, H. (2018). In vitro tools for the toxicological evaluation of sediments and dredged materials: intra-and inter-laboratory comparisons of chemical and bioanalytical methods. Environmental Science and Pollution Research, 25(5), 4037-4050.

Steffens, S., Nüßer, L., Seiler, T. B., Ruchter, N., Schumann, M., Döring, R., Cofalla, C., Ostfeld, A., Salomons, E., Schüttrumpf, H., Hollert, H. & Brinkmann, M. (2017). A versatile and low-cost open source pipetting robot for automation of toxicological and ecotoxicological bioassays. PloS one, 12(6), e0179636.

Nüßer, L. K., Skulovich, O., Hartmann, S., Seiler, T.-B., Cofalla, C., Schuettrumpf, H., Hollert, H., Salomons, E. & Ostfeld, A. (2016). A sensitive biomarker for the detection of aquatic contamination based on behavioral assays using zebrafish larvae. Ecotoxicology and environmental safety, 133, 271-280.

Xiao, H., Kuckelkorn, J., Nüßer, L. K., Floehr, T., Hennig, M. P., Roß-Nickoll, M., Schäffer, A. & Hollert, H. (2016). The metabolite 3, 4, 3ʹ, 4ʹ-tetrachloroazobenzene (TCAB) exerts a higher ecotoxicity than the parent compounds 3, 4-dichloroaniline (3, 4-DCA) and propanil. Science of the Total Environment, 551, 304-316.

Eichbaum, K., Brinkmann, M., Nuesser, L., Buchinger, S., Reifferscheid, G., Codling, G., Jones, P., Giesy, J. P., Hecker, M. & Hollert, H. (2016). Bioanalytical and instrumental screening of the uptake of sediment-borne, dioxin-like compounds in roach (Rutilus rutilus). Environmental Science and Pollution Research, 23(12), 12060-12074.

Schiwy, A., Brinkmann, M., Thiem, I., Guder, G., Winkens, K., Eichbaum, K., Nüßer, L., Thalmann, B., Buchinger S., Reifferscheid, G., Seiler, T. B., Thoms, B. & Hollert, H. (2015). Determination of the CYP1A-inducing potential of single substances, mixtures and extracts of samples in the micro-EROD assay with H4IIE cells. Nature protocols, 10(11), 1728.

Hug, C., Krauss, M., Nüsser, L., Hollert, H., & Brack, W. (2015). Metabolic transformation as a diagnostic tool for the selection of candidate promutagens in effect-directed analysis. Environmental pollution, 196, 114-124.