New publication online: S. Johann
A new publication of the Institute for Environmental Research is online:
Johann S. et al (2019): "Receptor-mediated estrogenicity of native and chemically dispersed crude oil determined using adapted microscale reporter gene assays" Environment International 134
Content: A study from the GRACE project investigated the estrogenic activity of dissolved oil compounds in the water phase underlying an oil slick. Validated microscale assays on estrogenicity were optimized for petroleum toxicity testing. Bioassays were highly sensitive towards WAF exposure in brackish and freshwater conditions. Native and chemically dispersed crude oil WAFs did activate the ERα. The dispersant itself had a limited influence on high CEWAF activity. Metabolization of WAF compounds did not change the estrogenic activity.