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postheadericon Research: Fate and Remediation

 

UBC - Chair of Environmental Biology and Chemodynamics

ESA - Department of Ecosystem Analysis

 

Anthropogenic chemicals are distributed on large areas (e.g., pesticides) or regionally (e.g., veterinary pharmaceuticals, heavy metals) in the environment.
Our group investigates the transformation of chemical compounds in the environment and in organisms, their binding and release into water, soil and the atmosphere. Regarding organisms we investigate the chemical, biochemical and genetic mechanisms of the uptake, transformation and immobilization of the chemicals. We are particularly interested in residues that cannot be extracted by solvents from soil or plants. Beside their chemical structure special interest focuses on the conditions necessary to render such 'bound residues' bioavailable for uptake by plants, animals or humans.
We develop bioremediation techniques to reduce the concentration of problematic compounds in contaminated soils and water using plants and microorganisms. One important aspect is the choice of plants, which should show a high tolerance and a high extraction potential regarding the contaminant. For that purpose, we profit from the potential of genetically modified plants.

 

Heads of research area

 

Topics

  • Phytoremediation
  • Fate and metabolism of xenobiotics in plants and plant cell cultures
  • Fate and metabolism of xenobiotics in soil and sewage sludge
  • Analysis of degradation products: TLC, HPLC, GC, GC-MS, UV/VIS
  • Fate and metabolism of endocrine disrupting chemicals in waste water treatment processes und in the environment
  • Molecular biological methods: Cloning, PCR, Western-Blottin
  • Molecular basis of insecticide resistance in insects
  • Chemical synthesis of isotope labelled model compounds
  • Characterization of bound residues of chemicals in soil and plants
  • Metabolism of xenobiotics by transgenic plant cell cultures and plants, experessing foreign cytochrome P450-monooxygenases

 

Projects


Biogenic formation of non-extractable residues from pesticides in soil (BioNER)

2012 - 2015



Siemens-Forschungsbereich "Rare Earths - Green Mining and Seperation"

2012 - 2015



Development of a biotest system to investigate the contamination level in soils by use of collembola as bioindicators

2012 - 2015



Nanorisk - Environmental risks of nanomaterials concerning real exposure-scenarios

2010 - 2013



CarboLifeCycle

2010 - 2013



Influence of microbial and enzymatic activities on immobilisation of xenobiotics in soil organo-clay complexes

2010 - 2012



Veterinary Medicines in Soils: Basic Research for Risk Analysis

2008 - 2011



Characterising the environmental behaviour and ecotoxicological potential of carbon nanotubes

2008 - 2012



Influence of microbial products on the structure-chemistry and chemodynamic of covalently immobilised residues of xenobiotics in soil derived organo-clay complexes

2007 - 2010



Metabolism of 14C-methoxychlor in human P450-transgenic and non-transgenic plant cell cultures for the production of endocrine active metabolites and their examination with regard to estrogenic activity

2006 - 2009



Fate of 17-ethinylestradiol in the aqueous environment and the associated effects on organisms

2005-2008



Das Schicksal von Tierantibiotika in güllegedüngten Böden

2005 - 2008



Oxidative metabolic profiling of xenobiotics using CYP1A1-, CYP1A2- and CYP3A4-transgenic plant cell cultures

2003 - 2008



The influence of sluge treatment on the fate of nonylphenol in sludge- amended soils

2004 - 2007



Transgenic plant cell suspension cultures as model systems for investigantions on the molecular mechanisms of insecticide resistance

2004 - 2007



Studies on the behaviour of endocrine disrupting compounds in a membrane bioreactor

2004 - 2007



Nonylphenol Metabolism of Sphingomonas TTNP3

2004 - 2007



Construction of a cDNA Library of Corn Cockle (Agrostemma githago L.) Cell Suspension Culture for the Screening for unknown P450 Sequences

2005 - 2006



Studies on the metabolic fate of 13C-nonylphenol in water and sediment and related microbial system

2004 - 2007



Behaviour and elimination of selected nonylphenol isomers in membrane-based model waste water treatment plants using 14C-labeled compounds

2003 - 2006



Immobilisation mechanisms of monomeric phenols in soil

2000 - 2006



The fate of Nonylphenol and Bisphenol A in sludge- amended soils

2002 - 2005



Influence of a recombinant human P450 system on endogenous compounds in transgenic plants of Nicotiana tabacum L.

2003 - 2004



Correlation of the degradation of endocrine disrupting compounds and the dissolved organic matter concentration in waste water

2001 - 2004



Balancing of the behaviour of hormone active synthetic chemicals by means of 14C-labeled compounds in model investigations concerning different steps of waste water treatment plants

1999 - 2004



Remobilisation of bound Simazine residues in soil

1998 - 2004



Bindung von Terbuthylazin-Metaboliten an gelöste organische Substanz (DOM) in Lysimetersickerwässern

2000 - 2003



Production of transgenic cell cultures of tobacco, which express the human cytochrome P450-monooxygenases CYP1A1 or CYP1A2

1999 - 2003



Einfluss von Tonmineralien auf die Bindung zweier Herbizid- Metaboliten an DOM

2001 - 2002



Characterisation of bound residues of the fungizide Cyprodinil

2001 - 2002



Interaction of 4-Nonylphenol und Bisphenol A with dissolved organic matter during wastewater treatment

1999 - 2002



Investigation on the structure and binding of non extractable residues and metabolism of the fungizide Cyprodinil in wheat

1999 - 2002



Investigation on the structure and binding of non extractable 15N- und 14C-Simazine residues in soil

1997 - 2002



Uptake, metabolism and formation of non-extractable residues of 4-nitrophenol in plant tissues

1995 - 2001



Glufosinate: Metabolism in transgenic and non-transgenic plant tissues, as well as fate in soil

1997 - 2000



Metabolism of [14C]-labelled n-Alkanes in Pseudomonas species allowing for the influence of rhamnolipids

1994 - 1997